CENPJ antibody (AA 675-725)
Quick Overview for CENPJ antibody (AA 675-725) (ABIN7453060)
Target
See all CENPJ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 675-725
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Purpose
- Rabbit anti-CENP-J Antibody, Affinity Purified
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Predicted Reactivity
- Chimpanzee
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Purification
- Affinity Purified
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Immunogen
- between AA 675 and 725
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Isotype
- IgG
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Application Notes
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IP: Not recommended
WB: 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CENPJ (Centromere Protein J (CENPJ))
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Alternative Name
- CENP-J
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Background
- Background: CENP-J is a centromeric protein that has been reported to play a role in mitosis and transcription. CENP-J plays a role in normal spindle morphology, transcription, cell signaling, and lysosomal trafficking. CENP-J is reported to be an inhibitor of microtubule assembly and may function to regulate microtubule dynamics at the centrosomes. In transcription, CENP-J functions as a coactivator in Stat5- and NF-kappaB-mediated transcription. Mutations in CENP-J are associated with autosomal recessive microcephaly.
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Gene ID
- 55835
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NCBI Accession
- NP_060921
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UniProt
- Q9HC77
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Pathways
- M Phase
Target
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